AskDefine | Define ligation

Dictionary Definition

ligation n : (surgery) tying a duct or blood vessel with a ligature (as to prevent bleeding during surgery)

User Contributed Dictionary




  1. Something that ties, a ligature.
  2. The act of tying, of applying a ligature.
  3. The state of having a ligature, of being tied.
  4. The act of tying off a blood vessel during surgery.

Extensive Definition

Ligation may refer to:
  • The act of making a ligature (tie). In medicine, a ligature is a device, similar to a tourniquet, usually of thread or string, tied around a limb, blood vessel or similar to restrict blood flow. A ligature can be used for tumor strangulation, carried out before removal.
  • Chemical ligation, the process of producing peptides from amino acids
  • The DNA-ligating action of DNA ligase
  • Tubal ligation, a method of female sterilization
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